The supplier of Pathlab’s total protein test has modified their calibrator to ensure traceability to the National Institute of Standards and Technology (NIST). This adjustment has resulted in a 4 per cent increase in total protein results. This change is within clinically acceptable limits, as determined by the College of American Pathologists (CAP).
Pathlab will be updating its total protein and globulin reference intervals, as well as the associated trigger values for recommending repeat testing and for protein electrophoresis.
For a period of three months, the following comment will appear on all total protein reports:
“TP results have increased by 4% following re-standardisation of the assay. The reference interval has been adjusted accordingly. The assay is otherwise unchanged.”
New reference intervals (effective Monday 3 November 2025)
| Test | Age range | Current ref interval | New ref interval | Units |
|---|---|---|---|---|
| Total protein | 0–5 months | 40–65 | 42–68 | g/L |
| Total protein | 6 months–1 year | 46–68 | 48–71 | g/L |
| Total protein | 1–2 years | 51–70 | 53–73 | g/L |
| Total protein | >2 years | 60–80 | 62–83 | g/L |
| Globulin | All ages | 25–41 | 27–43 | g/L |
These updates ensure continued accuracy and consistency with international standards.
This week the Pinnacle Incorporated Executive Committee has written to Dr Ashley Bloomfield, Director-General of Health and Labour MPs across the Midland region asking them to reconsider lowering the screening age for Māori and Pacific people.
Read morePathlab has had an equipment failure, compounded by a delayed replacement device delivery, impacting the following tests: Anti-TPO antibodies, CMV serology, EBV serology, Hepatitis B serology, Hepatitis A serology, Hepatitis C antibody, HIV serology, Rubella IgG, Syphilis screen and Toxoplasma serology. Please keep sending in the tests but expect an additional 1-2 weeks delay in reporting.
Read moreThe B4 School Check (B4SC) is a universal, comprehensive check for all four-year-old’s that includes height and weight, vision and hearing, immunisations, oral health, and behavioral and developmental components.
View detailsNational Cervical Screening Programme screening updates.